As in the case of disability, it is difficult to establish the threshold of activity that could predict a serious illness or not. The participation of a large number of joints, as well as large joints, would be related to a more serious evolution; on the contrary Keto Viante, those patients with few inflamed joints and of small size would have a better prognosis.
Biological markers of inflammation could be included within this context, since they usually run parallel to the clinical activity of the disease. Although there is no unanimity between the different studies, there does not appear to be substantial differences in the severity of the disease between the onset RA in the elderly (over 60-65 years) and in younger adults.
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